Selected Publications
1: McAfee Q, Chen CY, Yang Y, Caporizzo MA, Morley M, Babu A, Jeong S, Brandimarto J, Bedi KC Jr, Flam E, Cesare J, Cappola TP, Margulies K, Prosser B, Arany Z. Truncated titin proteins in dilated cardiomyopathy. Sci Transl Med. 2021 Nov 3;13(618):eabd7287. doi: 10.1126/scitranslmed.abd7287. Epub 2021 Nov 3. PMID: 34731015.
2: Caporizzo MA, Prosser BL. Need for Speed: The Importance of Physiological Strain Rates in Determining Myocardial Stiffness. Front Physiol. 2021 Jul 30;12:696694. doi: 10.3389/fphys.2021.696694. PMID: 34393820; PMCID: PMC8361601.
3: Shah PP, Lv W, Rhoades JH, Poleshko A, Abbey D, Caporizzo MA, Linares-Saldana R, Heffler JG, Sayed N, Thomas D, Wang Q, Stanton LJ, Bedi K, Morley MP, Cappola TP, Owens AT, Margulies KB, Frank DB, Wu JC, Rader DJ, Yang W, Prosser BL, Musunuru K, Jain R. Pathogenic LMNA variants disrupt cardiac lamina-chromatin interactions and de-repress alternative fate genes. Cell Stem Cell. 2021 May 6;28(5):938-954.e9. doi: 10.1016/j.stem.2020.12.016. Epub 2021 Feb 1. PMID: 33529599; PMCID: PMC8106635.
4: Chen CY, Salomon AK, Caporizzo MA, Curry S, Kelly NA, Bedi K, Bogush AI, Krämer E, Schlossarek S, Janiak P, Moutin MJ, Carrier L, Margulies KB, Prosser BL. Depletion of Vasohibin 1 Speeds Contraction and Relaxation in Failing Human Cardiomyocytes. Circ Res. 2020 Jul 3;127(2):e14-e27. doi: 10.1161/CIRCRESAHA.119.315947. Epub 2020 Apr 10. PMID: 32272864; PMCID:PMC7334093.
5: Mugnai ML, Caporizzo MA, Goldman YE, Thirumalai D. Processivity and Velocity for Motors Stepping on Periodic Tracks. Biophys J. 2020 Apr 7;118(7):1537-1551. doi: 10.1016/j.bpj.2020.01.047. Epub 2020 Feb 25. PMID: 32367805; PMCID: PMC7136348.
6: Caporizzo MA, Chen CY, Bedi K, Margulies KB, Prosser BL. Microtubules Increase Diastolic Stiffness in Failing Human Cardiomyocytes and Myocardium. Circulation. 2020 Mar 17;141(11):902-915. doi:10.1161/CIRCULATIONAHA.119.043930. Epub 2020 Jan 16. PMID: 31941365; PMCID:PMC7078018.
7: Parrish E, Caporizzo MA, Rose KA, Composto RJ. Erratum: "Network confinement and heterogeneity slows nanoparticle diffusion in polymer gels" [J. Chem. Phys. 146, 203318 (2017)]. J Chem Phys. 2020 Jan 31;152(4):049901. doi:10.1063/1.5142296. Erratum for: J Chem Phys. 2017 May 28;146(20):203318. PMID:32007059.
8: Caporizzo MA, Chen CY, Prosser BL. Cardiac microtubules in health and heart disease. Exp Biol Med (Maywood). 2019 Nov;244(15):1255-1272. doi: 10.1177/1535370219868960. Epub 2019 Aug 9. PMID: 31398994; PMCID: PMC6880149.
9: Caporizzo MA, Chen CY, Salomon AK, Margulies KB, Prosser BL. Microtubules Provide a Viscoelastic Resistance to Myocyte Motion. Biophys J. 2018 Nov 6;115(9):1796-1807. doi: 10.1016/j.bpj.2018.09.019. Epub 2018 Sep 28. PMID: 30322798; PMCID: PMC6224693.
10: Chen CY, Caporizzo MA, Bedi K, Vite A, Bogush AI, Robison P, Heffler JG, Salomon AK, Kelly NA, Babu A, Morley MP, Margulies KB, Prosser BL. Suppression of detyrosinated microtubules improves cardiomyocyte function in human heart failure. Nat Med. 2018 Aug;24(8):1225-1233. doi: 10.1038/s41591-018-0046-2. Epub 2018 Jun 11. PMID: 29892068; PMCID: PMC6195768.
11: Caporizzo MA, Fishman CE, Sato O, Jamiolkowski RM, Ikebe M, Goldman YE. The Antiparallel Dimerization of Myosin X Imparts Bundle Selectivity for Processive Motility. Biophys J. 2018 Mar 27;114(6):1400-1410. doi:10.1016/j.bpj.2018.01.038. PMID: 29590597; PMCID: PMC5883617.
12: Parrish E, Caporizzo MA, Composto RJ. Network confinement and heterogeneity slows nanoparticle diffusion in polymer gels. J Chem Phys. 2017 May 28;146(20):203318. doi: 10.1063/1.4978054. Erratum in: J Chem Phys. 2020 Jan 31;152(4):049901. PMID: 28571369.
13: Lee HS, Myers C, Zaidel L, Nalam PC, Caporizzo MA, A Daep C, Eckmann DM, Masters JG, Composto RJ. Competitive Adsorption of Polyelectrolytes onto and into Pellicle-Coated Hydroxyapatite Investigated by QCM-D and Force Spectroscopy. ACS Appl Mater Interfaces. 2017 Apr 19;9(15):13079-13091. doi: 10.1021/acsami.7b02774. Epub 2017 Apr 5. PMID:28332813.
14: Grady ME, Parrish E, Caporizzo MA, Seeger SC, Composto RJ, Eckmann DM. Intracellular nanoparticle dynamics affected by cytoskeletal integrity. Soft Matter. 2017 Mar 1;13(9):1873-1880. doi: 10.1039/c6sm02464e. PMID: 28177340; PMCID: PMC5333122.
15: Robison P, Caporizzo MA, Ahmadzadeh H, Bogush AI, Chen CY, Margulies KB, Shenoy VB, Prosser BL. Detyrosinated microtubules buckle and bear load in contracting cardiomyocytes. Science. 2016 Apr 22;352(6284):aaf0659. doi:10.1126/science.aaf0659. PMID: 27102488; PMCID: PMC5441927.
16: Nalam PC, Gosvami NN, Caporizzo MA, Composto RJ, Carpick RW. Nano-rheology of hydrogels using direct drive force modulation atomic force microscopy. Soft Matter. 2015 Nov 7;11(41):8165-78. doi: 10.1039/c5sm01143d. PMID: 26337502; PMCID: PMC4839974.
17: Caporizzo MA, Ezzibdeh RM, Composto RJ. Hierarchical nanoparticle topography in amphiphilic copolymer films controlled by thermodynamics and dynamics. Langmuir. 2015 Mar 17;31(10):3027-38. doi: 10.1021/la5045877. Epub 2015 Mar 2. PMID: 25689222; PMCID: PMC4839976.
18: Caporizzo MA, Roco CM, Ferrer MC, Grady ME, Parrish E, Eckmann DM, Composto RJ. Strain-rate Dependence of Elastic Modulus Reveals Silver Nanoparticle Induced Cytotoxicity. Nanobiomedicine (Rij). 2015;2:9. doi: 10.5772/61328. Epub 2015 Sep 2. PMID: 26834855; PMCID: PMC4732735.
19: Caporizzo MA, Sun Y, Goldman YE, Composto RJ. Nanoscale topography mediates the adhesion of F-actin. Langmuir. 2012 Aug 21;28(33):12216-24. doi: 10.1021/la302250x. Epub 2012 Aug 13. PMID: 22839968.